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Interferon-γ inducing polypeptide, pharmaceutical

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专利名称:Interferon-γ inducing polypeptide,

pharmaceutical composition thereof,monoclonal antibody thereto, and methodsof use

发明人:Shimpei Ushio,Kakuji Torigoe,Todao

Tanimoto,Haruki Okamura,MasashiKurimoto,Shigeharu Fukuda,ToshioKunikata,Mutsuko Taniguchi,Keizo Kohno

申请号:US09716356申请日:20001121公开号:US07135458B1公开日:20061114

摘要:A human IFN-γ inducing polypeptide and its nucleotide sequence was isolated,purified and characterized. Pharmaceutical compositions containing this novel IFN-γinducing polypeptide or active fragments thereof are formulated and monoclonalantibodies are raised against this polypeptide or antigenic fragments thereof. Thepolypeptide can be used in a method for treating diseases susceptive to treatment withIFN-γ, and methods for enhancing the cytotoxicity of NK cells or for inducing theformation of LAK cells, such as to treat tumors and malignant pathologies.

申请人:Shimpei Ushio,Kakuji Torigoe,Todao Tanimoto,Haruki Okamura,MasashiKurimoto,Shigeharu Fukuda,Toshio Kunikata,Mutsuko Taniguchi,Keizo Kohno

地址:Okayama JP,Okayama JP,Okayama JP,Osaka JP,Okayama JP,OkayamaJP,Okayama JP,Okayama JP,Okayama JP

国籍:JP,JP,JP,JP,JP,JP,JP,JP,JP

代理机构:Browdy and Neimark, PLLC

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