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DLL4-binding molecules

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专利名称:DLL4-binding molecules发明人:BORGES, ERIC,GSCHWIND,

ANDREAS,BOUCNEAU, JOACHIM,DETAVERNIER, EVELYN,KOLKMAN,

JOOST,MERCHIERS, PASCAL,VAN HOORICK,DIANE

申请号:AU2010302587申请日:20101001公开号:AU2010302587A1公开日:20120405

摘要:DII4-binding molecules, preferably DII4-binding immunoglobulin single variabledomains like VHHs and VHs, pharmaceutical compositions containing same and their usein the treatment of diseases that are associated with DII4-mediated effects onangiogenesis. Bispecific DII4-binding molecules that also bind to VEGF-A. Nucleic acidsencoding DII4-binding molecules, host cells and methods for preparing same.

申请人:BOEHRINGER INGELHEIM INTERNATIONAL GMBH

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