Pyrazole derivatives

专利名称：Pyrazole derivatives发明人：AKIO EJIMA,SATORU OHSUKI申请号：AU5577198申请日：19980126公开号：AU5577198A公开日：19980818

摘要：A compound represented by formula (I) or a salt thereof; wherein R<1> andR<2>, which may be the same or different, each represent a hydrogen atom, a halogenatom, a hydroxy group, an alkoxy group, an amino group, an alkylamino group, an arylgroup or an alkyl group; R<3> and R<4>, which may be the same, or different, eachrepresent a hydrogen atom, a halogen atom, an alkoxy group, an amino group, analkylamino group, an aryl group or an alkyl group; R<5> represents a hydrogen atom, analkyl group, an alkenyl group, an alkynyl group, an aryl group or an arylalkyl group; Qrepresents an amidino group, a cycloalkyl group, a phenyl group or amonocyclicheterocyclic group except a pyrimidinyl group bonded to the N atom at its 2-position; Grepresents a nitrogen-containing saturated heterocyclic structure represented byformula: wherein X<1> represents a nitrogen atom or CH, in which the ring may have aketo group and may have one or more substituents; Z represents a phenyl or

heterocyclic group which may have one or more substituents, in which two substituentson the phenyl or heterocyclic group may be connected to each other to form a ring toprovide a condensed bicyclic structure as a whole; the substituent on Z and thesubstituent on G may be connected to each other to form a condensed tricyclic ortetracyclic structure as a whole, and an antitumor agent containing the compound or a

salt thereof as an active ingredient.

申请人：DAIICHI PHARMACEUTICAL CO., LTD.

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