您的当前位置：首页 PREPARATION OF P-CHIROGENIC PHOSPHOLANES AND THEIR

PREPARATION OF P-CHIROGENIC PHOSPHOLANES AND THEIR

来源：尚车旅游网

专利内容由知识产权出版社提供

专利名称：PREPARATION OF P-CHIROGENIC

PHOSPHOLANES AND THEIR USE INASYMETRIC SYNTHESIS

发明人：HOGE, Garett Stewart, Pfizer Global Res. and

Dev.

申请号：EP05718265.1申请日：20050323公开号：EP1735324B1公开日：20080820

摘要：Materials and methods for preparing P-chirogenic monophospholanes andbisphospholanes are disclosed. The methods employ stereoselective cyclization togenerate the phospholane rings followed by pyramidal inversion to access a variety of P-chirogenic phospholanes. When bound to transition metals such as rhodium, the

disclosed P-chirogenic phospholanes may be used as catalysts in asymmetric synthesis ofvaluable pharmaceutical chemical entities, including pregabalin.

申请人：WARNER LAMBERT CO

地址：US

国籍：US

代理机构：Hodge, Emma Jane

更多信息请下载全文后查看

因篇幅问题不能全部显示，请点此查看更多更全内容

查看全文