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OXADIAZOLE BETA CARBOLINE DERIVATIVES AS ANTIDIABE

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专利名称:OXADIAZOLE BETA CARBOLINE

DERIVATIVES AS ANTIDIABETICCOMPOUNDS

发明人:GUO, LIANGQIN,HAGMANN, WILLIAM, K.,HE,

SHUWEN,LAI, ZHONG,LIU, JIAN,NARGUND,RAVI, P.,SHAH, SHRENIK, K.,TRUONG,QUANG, T.

申请号:EP11733256申请日:20110111公开号:EP2523558A4公开日:20130619

摘要:Beta-carboline derivatives of structural formula I are selective antagonists ofthe somatostatin subtype receptor 3 (SSTR3) and are useful for the treatment of Type 2diabetes mellitus and of conditions that are often associated with this disease, includinghyperglycemia, insulin resistance, obesity, lipid disorders, and hypertension. Thecompounds are also useful for the treatment of depression and anxiety.

申请人:MERCK SHARP & DOHME CORP.

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